Mark Kendall: Demo: A needle-free vaccine patch that's safer and way cheaper
Mark Kendall - Biomedical engineer
Mark Kendall aims to shake up how vaccines are delivered with the Nanopatch. Full bio
this 160-year-old technology.
of the rollout of vaccines.
you probably may have heard of,
may not have heard about.
that I'll tell you about as well.
tackle those four problems.
work with the skin's immune system.
is one that's been borrowed
the projections of the Nanopatch
the Nanopatch to the skin as so --
a reuse of the applicator itself.
responses through delivery,
this immunogenicity idea.
how to deal with intruders.
with the needle and syringe,
is holding back our immune responses;
going 10 times deeper as well.
have those projections in the skin.
called a Langerhans cell --
there's others shown as well
of these particular cells
this thing and designed it to do that,
the dose shown in nanograms.
the immune response generated,
the protection threshold.
is achieved with the needle that's protective,
that works but is too expensive
compared to the needle.
10 dollars down to 10 cents,
within the developing world.
7 million deaths per year,
method for any of those.
that we have with the Nanopatch,
candidate vaccines over the line.
a vaccine right from production
cold chain has fallen over.
in with the needle and syringe
when it's liquid it needs the refrigeration.
any loss in activity at all.
we have well and truly proven
out, taken it out of the lab
journey in an unusual way.
of a developing world country.
refrigerators to keep vaccines chilled.
many of them are breaking down
where they are required.
world's highest incidence of HPV,
cervical cancer [risk factor].
the attributes of the Nanopatch,
worked with the Nanopatch,
the world I'd rather be doing.
of being needle-free, pain-free,
and improving the immunogenicity.
About the speaker:Mark Kendall - Biomedical engineer
Mark Kendall aims to shake up how vaccines are delivered with the Nanopatch.
Why you should listen
Looking a bit like a fuzzy computer chip, the Nanopatch uses tiny powder-coated spikes to deliver a small dose of vaccine just under the skin, immunizing a person in about a minute. Made for less than $1, it uses only a fraction of a vaccine dose delivered by traditional syringe method (which was invented in 1853), at the same time eliminating the risk of needle injuries. What’s more, a Nanopatch infused with vaccine is designed to be heat-stable, so it can be transported without refrigeration. And the process doesn't draw blood, reducing the risk of infections.
Mark Kendall, an Australian biomedical engineer, was part of a team at the University of Queensland that advanced the Nanopatch by vaccinating animals. Now his company, Vaxxas, is on a mission to commercialize the device for human use. He plans to run an international trial using the Nanopatch, starting with the human papilloma virus (HPV) vaccine to protect against cervical cancer.
Mark Kendall | Speaker | TED.com