Kevin B. Jones: Why curiosity is the key to science and medicine
Kevin B. Jones - Cancer researcher
Kevin B. Jones is a life-long student of human nature, fascinated most by the decision-making capacity intrinsic to each of us. Full bio
unhappy memories of boredom
of what other people had discovered.
guess an explanation for that observation,
that we can test
that the Earth was below, the sky above,
seemed to go around them.
the center of the universe.
should circle around the Earth.
on one of the first telescopes,
to follow the path of Jupiter
also was not going around the Earth
the discarding of the theory
of the universe.
noticed that things fall to the Earth.
should fall to the Earth.
does fall to the Earth.
gravity pulls things to the Earth
and opposite force in the other direction.
to the bird and the bird's wings,
from that line of thinking.
the exceptions, the outliers
and lead us to something new.
This is how science learns.
and even more rarely,
has been scientifically proven.
that science never proves anything
here for a second.
to different people,
public discourse on medicine
an engineering problem.
that try to figure out how to pay for it.
how best to distribute medicine,
are absolutely obsessed
how best to safely apply medicine.
the quality of our health care
that in this climate,
for the provision of health care
like Jiffy Lube.
when I graduated from medical school,
has to plug into your car
of that observation,
that we can test.
of most predictions in medicine
from those boring days in biology class
from a guessed explanation,
of my patients is an outlier,
for a sarcoma patient
by a randomized controlled clinical trial,
of population-based evidence in medicine.
outside the box,
a bath in the uncertainty
and outliers that surround us in sarcoma
are those two most important values
albeit distinct patient with sarcoma.
to talk to each other through chat rooms
of humbly curious communication
the ankle to serve as the knee
with the cancer.
and run and jump and play.
who had experienced it.
but also lead us to new thinking.
and exceptions lead us to in medicine
to the outliers and exceptions.
from sarcoma patients
to the general population.
draw our attention
of perhaps what a tree is.
losing the forests for the trees,
that define a tree,
and roots and branches,
has very unusual relationships
in the general population.
of all cancers.
is considered a genetic disease.
that cancer is caused by oncogenes
that are turned off to cause cancer.
that we learned about oncogenes
from common cancers
and tumor suppressor genes
of cancers called sarcoma.
and Mike Bishop discovered
that src is the most important oncogene.
turned on oncogene in all of cancer.
about the rest of biology.
tumor suppressor gene.
tumor suppressor gene
from common cancers.
when doctors Li and Fraumeni
in a million diagnosis,
about a bird's wing.
floating around some planet Jupiter.
may lead to the advancement of science,
with rare and deadly diseases.
or "There's nothing more we can do."
turn on a single word:
in these conversations.
that are being done?
you see this phrase, "no where."
one of my patients' rooms.
with a bone cancer a few days before.
with the chemotherapy doctors
to the hospital to begin chemotherapy.
when I got to his room.
to chat with me for a few minutes.
what she had been reading
that the chemotherapy doctors
and I think I can do it.
with these very difficult treatments.
I'm going to move in with my parents.
matter in my life."
a whole lot in your life.
we test predictions in populations,
embedded in the general population,
nor the physician knows
the individual will land.
a better or a worse result for you.
removed a tumor from a patient's limb.
he talked about his concern
for coming back in the same limb.
and you're good to go."
opened a bottle of champagne.
another nodule in the same area.
and she wasn't good to go.
absolutely fascinates me.
looking after this patient for me?"
to do as well as I do.
after this patient for me."
a much more invasive surgery
with the patient afterwards.
that we're doing.
to find out if this surgery will work
after talking to me.
will be that patient sometime very soon.
About the speaker:Kevin B. Jones - Cancer researcher
Kevin B. Jones is a life-long student of human nature, fascinated most by the decision-making capacity intrinsic to each of us.
Why you should listen
Kevin B. Jones diagnoses and performs surgeries to remove rare cancers called sarcomas from the limbs of children and adults. Counseling patients -- especially teenagers with bone cancers -- about the decisions they must make with regard to their bodies has brought the uncertainties of medicine into keen focus for him. How does a person decipher what medicine has told her? How can a person choose among options given very limited understanding of the implications of each? Intrigued by these riddles and conundrums that patient-physician communication frequently creates, Jones wrote a book, What Doctors Cannot Tell You: Clarity, Confidence and Uncertainty in Medicine.
Jones also runs a scientific research laboratory focused on the biology of sarcomas. Here, his team studies the decisions cells make on the way to becoming a cancer. Again the complexities and uncertainties inherent to these decisions are in full relief.
Jones sees patients and does surgery as an associate professor at the University of Utah in the Department of Orthopaedics, working at both Primary Children's Hospital and the Huntsman Cancer Institute. His laboratory is in the Huntsman Cancer Institute, where he is an adjunct faculty member in the Department of Oncological Sciences.
Jones studied English literature at Harvard, medicine at Johns Hopkins, orthopedic surgery at the University of Iowa, and musculoskeletal oncology at the University of Toronto. He lives in Salt Lake City with his wife and four children.
Kevin B. Jones | Speaker | TED.com