Siddharthan Chandran: Can the damaged brain repair itself?
Siddharthan Chandran - Regenerative neurologist
Siddharthan Chandran explores how to heal damage from degenerative disorders such as MS and motor neuron disease (ALS). Full bio
damage -- atrophy, scarring.
symphony of electrical activity,
about what were his problems
caught all of that, but what John was telling us
further down in that journey,
the breathing's gotten worse.
my arms and my legs.
consequence of the disease,
things I want to show you.
just doesn't do it well enough.
of travel for new therapies --
repair that occurs anyway.
about 10,000 compounds
early in drug discovery.
study of mankind is man,
several major discoveries
from anybody in this room,
it, me and medical school? —
on his present showing this is quite ridiculous."]
got the Nobel Prize for medicine
Steve Finkbeiner and Tom Maniatis.
grow and put out processes,
track their individual health
this was successful or not,
the optic nerve is shrinking,
About the speaker:Siddharthan Chandran - Regenerative neurologist
Siddharthan Chandran explores how to heal damage from degenerative disorders such as MS and motor neuron disease (ALS).
Why you should listen
Multiple sclerosis (MS) affects the nervous system by chewing up the axons that connect neurons to one another, which slows, stops or simply randomizes the transmission of nerve impulses. At the Centre for clinical brain sciences at the University of Edinburgh, Siddharthan Chandran works in the emerging discipline of regenerative neurology -- exploring how injured or damaged neurons in the brain might actually be repaired.
His research strategy uses MS and motor neuron disease (ALS, or Lou Gehrig's diesease) as primary disease models, combining laboratory and clinical activity to study brain injury, neurodegeneration and repair, using stem cells to model and test. His work, he says, "reflects the complexity of the brain. You can replace a kidney, but not a brain. One must remain careful and humble in the face of current knowledge." He is also director of the Anne Rowling Regenerative Neurology Clinic.
Siddharthan Chandran | Speaker | TED.com