Laura Indolfi: Good news in the fight against pancreatic cancer
Laura Indolfi: Boas notícias na luta contra o cancro do pâncreas
Laura Indolfi is revolutionizing cancer treatment with new technologies including implantable devices for delivering drugs locally to the site of a tumor. Full bio
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at least one person on the screen?
in their fields.
nas suas áreas.
all of them have in common?
de cancro no pâncreas.
very sad this news,
sejam notícias muito tristes,
of how lethal this disease can be.
de como perigosa pode ser esta doença.
of cancer deaths,
will survive beyond five years.
vão sobreviver ao fim de cinco anos.
with breast cancer,
com o cancro da mama,
is almost 90 percent.
é quase 90%.
with pancreatic cancer
certain death sentence.
uma sentença de morte.
is that in the last 40 years,
é que nos últimos 40 anos,
nem um bocadinho,
treatment more effective?
o tratamento do cancro pancreático?
that seem impossible,
que parecem ser impossíveis,
with pancreatic cancer
com o cancro do pâncreas
of your belly, literally.
da nossa barriga, literalmente.
organs in front.
os outros órgãos em frente dele.
by many other vital organs,
por muitos outros órgãos vitais,
the bile duct.
o ducto biliar.
to grow into those organs
para invadir esses órgãos
also prevents the doctor
for breast cancer, for example.
para o cancro da mama, por exemplo.
chemotherapy as the only option
deixam a quimioterapia como a única opção
piece of bad news.
das más notícias.
very few blood vessels.
têm muito poucos vasos sanguíneos.
about the blood vessel of a tumor?
com os vasos sanguíneos de um tumor?
how chemotherapy works.
em como funciona a quimioterapia.
until it reaches the tumor site.
até que chega ao local do tumor.
trying to reach a destination.
tentando chegar ao destino.
doesn't have an exit on the highway?
uma saída na autoestrada?
throughout all of your body.
por todo o nosso corpo.
for the patients overall,
para os doentes, no geral,
vai chegar ao tumor.
to have a whole-body treatment
fazer um tratamento de corpo inteiro
and effort have gone towards
investigação e empenho
to treat pancreatic cancer,
e poderosos para o cancro pancreático,
in changing the way
de más noticias,
good news, hopefully.
General Hospital in Boston,
Hospital, em Boston,
the way we treat cancer
como tratamos o cancro
drug delivery a reality.
localizada do medicamento.
on top of your destination,
de paraquedas no destino,
all around the highway.
into devices that look like this one.
em dispositivos como este.
that they can be folded
directly on top of the tumor
diretamente no tumor
cirúrgica minimamente invasiva.
that once they are positioned
physically prevent the tumor
slowly and more effectively
com o atual método de corpo inteiro.
we have demonstrated
the response to treatment.
a resposta ao tratamento.
where it's needed the most,
onde era mais preciso,
that is 12 times more powerful,
12 vezes mais forte,
this technology to the next level.
ao nível seguinte.
prior to asking the FDA for approval
para pedir a aprovação da FDA
will die from pancreatic cancer.
de cancro pancreático irá morrer.
extend their life
prolongar a vida deles
tornar o cancro pancreático
de administrar o medicamento,
more powerful and less toxic,
e menos tóxico
to finding new innovative solutions
para encontrar soluções inovadoras
os outros problemas impossíveis
e não só.
ABOUT THE SPEAKERLaura Indolfi - Biomedical entrepreneur
Laura Indolfi is revolutionizing cancer treatment with new technologies including implantable devices for delivering drugs locally to the site of a tumor.
Why you should listen
Laura Indolfi is a biomedical entrepreneur, CEO and co-founder of PanTher Therapeutics, an early stage spin-out from MIT and MGH that provides superior technologies for revolutionizing the treatment of locally advanced inoperable solid tumors. Prior to this she served as an entrepreneur-in-residence at the MGH Cancer Center and as a research associate in the Harvard-MIT Institute for Medical Engineering and Science. She was selected as a TED Fellow in 2016.
Indolfi has broad professional experiences and interests ranging from biomedical engineering to entrepreneurship and outreaching initiative to promoting science. Her scientific expertise covers a broad range of therapeutic areas (cardio, cancer, inflammation, regenerative medicine) and approaches (drug delivery, cell therapy, implanted devices). Together with her strong technical background, Laura has hands-on business and managerial know-how developed during her biomedical business training at Sloan and Harvard Business Schools and with several consulting firms. She strongly believes in the power of outreach initiatives to promote research awareness and foster the public audience's discovery of the beauty of science. In 2014 the line of clothes Cytocouture, created in collaboration with Colombian designer Carlos Villamil and inspired by her cell-therapy research, won the global competition Descience.
Indolfi holds a MS/BS degree in materials science and engineering and a PhD in biomaterials from the University of Naples Federico II in Italy. Upon graduation, she joined the Harvard-MIT Division of health, science and technology, working on several projects spanning from devices for local drug delivery to tissue engineering approaches for cell therapies.
Laura Indolfi | Speaker | TED.com