John Amory: How a male contraceptive pill could work
约翰·埃默里 (John Amory): 男性避孕药会如何起效
John Amory is leading research into novel options for male contraception, male infertility and hypergonadism. Full bio
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a contraceptive pill for men,
along gender lines.
I have in store for their testicles.
annually in the United States,
of the more than one million abortions
has fallen in the last few years
are using effective, long-acting,
becoming a real possibility
of contraception for women:
shots, sponges, rings, etc.
for 30 percent of all contraceptive use,
relying on vasectomy
relying on condoms for contraception
failure rate of over 15 percent?
失败率超过了 15% ？
can't either safely take
for reasons such as blood clots,
would be useful, the next question is:
swim towards or bind to the egg.
to be really difficult,
in the small volume of the ejaculate
the female reproductive tract.
done on the second approach,
sperm production entirely.
that men make a lot of sperm.
of sperm production
hormones to suppress sperm production.
when administered together,
to the testes to make sperm,
three to four months will stop.
don't respond to these hormonal regimens
my colleagues and I
to male contraceptive development,
the administration of hormones.
the function of vitamin A in the testes.
it's been known
of vitamin A in their diet
when the vitamin A is reintroduced.
to something called retinoic acid.
is found only in the testes.
that we are attempting to block.
should deprive the testes of retinoic acid
elsewhere in the body.
of such a male contraceptive
about the effect that it would have
his contraceptive status over time.
home sperm-testing devices
and share the result with his partner.
would feel very comfortable
coupled with a male contraceptive,
in preventing unintended pregnancy.
on male contraception
a better future for couples,
considered just "a woman's issue,"
for couples to decide together.
rates of unintended pregnancy and abortion
ABOUT THE SPEAKERJohn Amory - Male reproductive health expert
John Amory is leading research into novel options for male contraception, male infertility and hypergonadism.
Why you should listen
John Amory is is currently examining the potential of using inhibitors of testicular retinoic acid biosynthesis as reversible male contraceptives. He has published more than 130 peer-reviewed papers in the field of male reproduction and serves on the Advisory Board of the Male Contraception Initiative. He is currently Professor of Medicine and Section Head of General Internal Medicine at the University of Washington, where he works as an attending physician on the inpatient medicine wards and in the outpatient General Internal Medicine and Men's Health Clinics.
John Amory | Speaker | TED.com